Sugi Predict

Sugi Predict / Compounds / SCHEMBL3996360

SCHEMBL3996360

SCHEMBL3996360

CCCCC(N)(N)C(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FDPS P14324 3/20 0.39
▸ DGAT1 O75907 1/20 0.38
▸ SMPD1 P17405 4/20 0.34
▸ CTSK P43235 4/20 0.34
▸ LMNA P02545 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ CTSS P25774 1/20 0.32
▸ CA1 P00915 2/20 0.32
▸ CA12 O43570 1/20 0.32
▸ CA7 P43166 1/20 0.32
▸ CA14 Q9ULX7 1/20 0.32
▸ CA2 P00918 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ ATM Q13315 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ CYP4F2 P78329 1/20 0.31
▸ CYP4A11 Q02928 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150072 0.94 FDPS (0.41) FDPSDGAT1SMPD1MEN1MAPT
SCHEMBL29087510 0.92 SMPD1 (0.43) FDPSSMPD1MEN1MAPTKMT2A
Hydrochloric Acid SCHEMBL2418361 0.92 FDPS (0.40) FDPSDGAT1SMPD1CTSKMEN1
SCHEMBL10706328 0.92 SMPD1 (0.43) FDPSSMPD1MEN1MAPTKMT2A
SCHEMBL3127114 0.88 DGAT1 (0.40) FDPSDGAT1LMNAHSD17B10CA1
SCHEMBL29503885 0.84 FDPS (0.39) FDPSDGAT1SMPD1CTSKLMNA
SCHEMBL6535584 0.82 FDPS (0.38) FDPSDGAT1SMPD1CTSKLMNA
SCHEMBL15415012 0.82 DGAT1 (0.36) FDPSDGAT1LMNAMEN1MAPT
SCHEMBL10654172 0.81 ALDH1A1 (0.36) DGAT1LMNAHSD17B10MEN1KMT2A
SCHEMBL345584 0.79 FDPS (0.36) FDPSDGAT1SMPD1CTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024221952-A1 NANO-DELIVERY SYSTEM OF NUCLEOTIDE DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国科学院苏州纳米技术与纳米仿生研究所 2024-10-31 — — WO claimed
EP-4707404-A2 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION Ventana Medical Systems, Inc. (US) 2026-03-11 — — EP disclosed
EP-3492919-B1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION VENTANA MED SYST INC (US) 2026-01-21 — — EP disclosed
EP-4527828-A1 BIPHENYL COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF Longivitron (Suzhou) Biotechnology Co., Ltd (CN) 2025-03-26 — — EP disclosed
CN-119241502-B NSD3 degradation agent and preparation method and application thereof 四川大学华西医院 2025-02-28 — — CN disclosed
US-12215118-B2 Quinone methide analog signal amplification VENTANA MEDICAL SYSTEMS, INC. (US) 2025-02-04 — — US disclosed
CN-119241502-A NSD3 degradation agent and preparation method and application thereof 四川大学华西医院 2025-01-03 — — CN disclosed
WO-2024221952-A1 NANO-DELIVERY SYSTEM OF NUCLEOTIDE DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国科学院苏州纳米技术与纳米仿生研究所 2024-10-31 — — WO disclosed
US-20240018174-A1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION VENTANA MED SYST INC (US) 2024-01-18 — — US disclosed
US-11867698-B2 Fluorogenic pH sensitive dyes and their method of use Life Technologies Corporation (US) 2024-01-09 — — US disclosed
US-9939454-B2 Fluorogenic pH sensitive dyes and their method of use Life Technologies Corporation (US) 2018-04-10 — — US disclosed
US-9910051-B2 Fluorogenic pH sensitive dyes and their method of use Life Technologies Corporation (US) 2018-03-06 — — US disclosed
US-20160139158-A1 FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE Life Technologies Corporation 2016-05-19 — — US disclosed
US-20150037834-A1 FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE Life Technologies Corporation 2015-02-05 — — US disclosed
EP-2727965-A1 Fluorogenic pH sensitive dyes and their method of use Life Technologies Corporation (US) 2014-05-07 — — EP disclosed
EP-2064290-B1 FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE LIFE TECHNOLOGIES CORP (US) 2013-10-09 — — EP disclosed
US-20130102021-A1 FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE Life Technologies Corporation (US) 2013-04-25 — — US disclosed
EP-2064290-A2 FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE Life Technologies Corporation (US) 2009-06-03 — — EP disclosed
US-20080274907-A1 FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE INVITROGEN CORPORATION (US) 2008-11-06 — — US disclosed
WO-2008076524-A2 FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE Life Technologies Corporation (US) 2008-06-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274907-A1 FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE SLC11A2, MAN2B1, CD47 FDPS 354/4885DGAT1 2845/4885SMPD1 37/4885
US-12215118-B2 Quinone methide analog signal amplification NQO2, SQOR, MRM1 FDPS 2055/4885DGAT1 3557/4885SMPD1 1888/4885
US-20240018174-A1 QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION NQO2, SQOR, MRM1 FDPS 2055/4885DGAT1 3557/4885SMPD1 1888/4885
US-11867698-B2 Fluorogenic pH sensitive dyes and their method of use SLC11A2, MAN2B1, CD47 FDPS 354/4885DGAT1 2845/4885SMPD1 37/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.