Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4006094 | 0.86 | EPHX2 (0.47) | ALDH1A1TSHR | |
| SCHEMBL4003899 | 0.85 | EPHX2 (0.49) | KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL4007565 | 0.85 | POLB (0.45) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL4009618 | 0.79 | PKM (0.40) | NPC1 | |
| SCHEMBL4005131 | 0.78 | EPHX2 (0.47) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL4006918 | 0.77 | ALDH1A1 (0.45) | KMT2AADORA3ALDH1A1TSHR | |
| SCHEMBL4010821 | 0.77 | KMT2A (0.37) | KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL4010678 | 0.77 | HSD11B1 (0.45) | TSHR | |
| SCHEMBL4003470 | 0.76 | CTSS (0.39) | — | |
| SCHEMBL4001738 | 0.76 | EPHX2 (0.47) | KMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | claimed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | claimed |