Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609897 | 0.81 | MAPT (0.41) | MEN1KMT2A | |
| SCHEMBL3998980 | 0.76 | NPC1 (0.30) | — | |
| SCHEMBL1611886 | 0.76 | ALDH1A1 (0.36) | KDM4EMEN1KMT2ANOTUM | |
| SCHEMBL1957347 | 0.75 | ALDH1A1 (0.33) | KDM4EMEN1KMT2A | |
| SCHEMBL4007088 | 0.75 | ALDH1A1 (0.34) | KDM4EMEN1KMT2A | |
| SCHEMBL472288 | 0.71 | MAPT (0.37) | MEN1KMT2A | |
| SCHEMBL472625 | 0.71 | LMNA (0.42) | — | |
| SCHEMBL1610695 | 0.70 | HTT (0.39) | — | |
| SCHEMBL16680958 | 0.70 | RXRA (0.40) | XDHKDM4E | |
| SCHEMBL472629 | 0.69 | MAPT (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069338-A1 | INSECTICIDAL ISOXAZOLINES | Bayer CropScience AG (DE) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008019760-A1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |