Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4968182 | 0.85 | PDE3B (0.31) | — | |
| SCHEMBL472625 | 0.82 | LMNA (0.42) | HPGDSMN1; SMN2 | |
| SCHEMBL472288 | 0.82 | MAPT (0.37) | — | |
| SCHEMBL472629 | 0.81 | MAPT (0.34) | NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL739419 | 0.81 | USP2 (0.32) | — | |
| Ammonia Solution, Strong SCHEMBL27964641 | 0.80 | MAPT (0.33) | NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL472676 | 0.79 | NCOA1 (0.33) | HPGDSMN1; SMN2 | |
| SCHEMBL19723063 | 0.79 | USP2 (0.31) | — | |
| SCHEMBL3116206 | 0.79 | VCAM1 (0.44) | HPGDSMN1; SMN2 | |
| SCHEMBL737953 | 0.79 | NPC1 (0.35) | NPC1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069338-A1 | INSECTICIDAL ISOXAZOLINES | Bayer CropScience AG (DE) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008019760-A1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |