SCHEMBL472629

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Ammonia Solution, Strong SCHEMBL27964641	0.99	MAPT (0.33)	MAPTSMN1; SMN2ALDH1A1LMNANPC1
	SCHEMBL14046760	0.95	MAPT (0.33)	MAPTSMN1; SMN2ALDH1A1LMNANPC1
	SCHEMBL737953	0.92	NPC1 (0.35)	MAPTSMN1; SMN2LMNANPC1RAB9A
	SCHEMBL472625	0.90	LMNA (0.42)	MAPTSMN1; SMN2ALDH1A1LMNAHTT
	SCHEMBL472288	0.90	MAPT (0.37)	MAPTALDH1A1LMNAHTTMEN1
	SCHEMBL472676	0.88	NCOA1 (0.33)	MAPTSMN1; SMN2LMNAHTTUSP2
	SCHEMBL739419	0.88	USP2 (0.32)	MAPTLMNAHTTUSP2CA1
	SCHEMBL3116206	0.86	VCAM1 (0.44)	MAPTSMN1; SMN2LMNAHTTUSP2
	SCHEMBL19723063	0.86	USP2 (0.31)	MAPTLMNAHTTUSP2
	SCHEMBL1795659	0.86	ALOX12 (0.33)	MAPTUSP2HPGDCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.