Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13769525 | 0.87 | MAPT (0.40) | MAPTSRCCNR1CNR2KDM4E | |
| SCHEMBL4007615 | 0.86 | SRC (0.43) | EGLN1MAPTPOLBCCR4SRC | |
| SCHEMBL4014280 | 0.84 | EGLN1 (0.34) | EGLN1MAPTPOLBCCR4SRC | |
| SCHEMBL4008754 | 0.83 | FLT4 (0.44) | ABL1EGLN1MAPTPOLBCCR4 | |
| SCHEMBL4006132 | 0.83 | P2RX7 (0.43) | EGLN1MAPTPOLBSRCKDM4E | |
| SCHEMBL13769690 | 0.81 | STAT3 (0.38) | EGLN1MAPTPOLBSRCPTGDR2 | |
| SCHEMBL4006629 | 0.80 | MAPT (0.38) | MAPTPOLBCCR4SRCCNR1 | |
| SCHEMBL4005788 | 0.80 | MAPT (0.43) | MAPTKDM4EALDH1A1ADK | |
| SCHEMBL4006053 | 0.79 | LMNA (0.47) | MAPTPOLBCNR1CNR2KDM4E | |
| SCHEMBL4013415 | 0.78 | LMNA (0.39) | MAPTPOLBCNR1CNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080682-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |