Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008416 | 0.90 | CCR4 (0.39) | SRCMEN1NR2F2KMT2AP2RX7 | |
| SCHEMBL4006132 | 0.87 | P2RX7 (0.43) | SRCEGLN1POLBMAPTP2RX7 | |
| SCHEMBL4007097 | 0.86 | ALOX15 (0.36) | SRCEGLN1POLBMAPTNOTUM | |
| SCHEMBL4014280 | 0.86 | EGLN1 (0.34) | SRCMEN1NR2F2KMT2AEGLN1 | |
| SCHEMBL4008754 | 0.85 | FLT4 (0.44) | SRCEGLN1POLBMAPTMCL1 | |
| SCHEMBL13769690 | 0.85 | STAT3 (0.38) | SRCEGLN1POLBMAPTNOTUM | |
| SCHEMBL4005788 | 0.84 | MAPT (0.43) | MAPTADK | |
| SCHEMBL13769532 | 0.84 | PDE4B (0.41) | SRCMEN1NR2F2KMT2AMAPT | |
| SCHEMBL4006053 | 0.83 | LMNA (0.47) | MEN1KMT2APOLBMAPT | |
| SCHEMBL4013415 | 0.81 | LMNA (0.39) | MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080682-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |