Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007615 | 0.85 | SRC (0.43) | EGLN1POLBMAPTSRCNOTUM | |
| SCHEMBL4002268 | 0.85 | CNR1 (0.36) | PIK3CDCFDKLKB1BCL6 | |
| SCHEMBL4006132 | 0.82 | P2RX7 (0.43) | EGLN1POLBMAPTSRCADK | |
| SCHEMBL4014280 | 0.81 | EGLN1 (0.34) | PTGDR2EGLN1POLBMAPTSRC | |
| SCHEMBL4007097 | 0.81 | ALOX15 (0.36) | PTGDR2EGLN1POLBMAPTSRC | |
| SCHEMBL4008754 | 0.80 | FLT4 (0.44) | EGLN1POLBMAPTSRCADK | |
| SCHEMBL4005788 | 0.79 | MAPT (0.43) | MAPTADK | |
| SCHEMBL4006053 | 0.78 | LMNA (0.47) | POLBMAPTLRRK2 | |
| SCHEMBL4013415 | 0.77 | LMNA (0.39) | POLBMAPTLRRK2 | |
| SCHEMBL4010459 | 0.77 | MAPT (0.41) | POLBMAPTLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080682-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |