Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
| ▸ | MAP3K11 | Q16584 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009811 | 0.87 | MCHR1 (0.49) | ADORA2AADORA1MCHR1MAP3K11 | |
| SCHEMBL3927916 | 0.76 | ATR (0.48) | ADORA2AADORA1MCHR1MAP3K11 | |
| SCHEMBL4006573 | 0.76 | ATR (0.59) | ACHE | |
| SCHEMBL4009857 | 0.75 | MCHR1 (0.51) | ADORA2AADORA1MCHR1MAP3K11ACHE | |
| SCHEMBL4004985 | 0.75 | ATR (0.47) | ADORA2AADORA1MCHR1MAP3K11 | |
| SCHEMBL4008321 | 0.74 | ATR (0.55) | ADORA2AADORA1MCHR1MAP3K11 | |
| SCHEMBL4012928 | 0.72 | ATR (0.54) | ADORA2AADORA1MCHR1MAP3K11 | |
| SCHEMBL30424886 | 0.72 | AMY1A (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9025017 | 0.70 | ACHE (0.59) | ADORA2AACHETLR8TLR7 | |
| SCHEMBL14767414 | 0.70 | MCHR1 (0.56) | ADORA2AADORA1MCHR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007390-A2 | 2-PYRAZ INYLBENZ IMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | WO | claimed |