Hydrochloric Acid

Hydrochloric Acid

SCHEMBL401023

CC(C)(C)c1ccc2c(c1)-c1cc(C(C)(C)C)ccc1C2[Zr+2](C1=CC=CC1)=C(c1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1.[Cl-].[Cl-]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 3/20 0.38
CES2 O00748 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
TAS1R2 Q8TE23 1/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
TP53 P04637 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CNR2 P34972 2/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL399900 0.97 ACHE (0.36) ACHECES2TAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL396692 0.94 CCR2 (0.36) ACHECES2TAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL398764 0.93 ACHE (0.38) ACHECES2TAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL401779 0.92 ACHE (0.32) ACHE
Hydrochloric Acid SCHEMBL399876 0.91 TRPV1 (0.32) ACHE
Hydrochloric Acid SCHEMBL397052 0.90 ACHE (0.36) ACHECES2TAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL400800 0.90 CES2 (0.33) ACHECES2TAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL401687 0.90 ACHE (0.33) ACHE
Hydrochloric Acid SCHEMBL401429 0.89 CNR2 (0.35) ACHECNR2
Hydrochloric Acid SCHEMBL18280821 0.89 RBP4 (0.35) CES2TAS1R3TAS1R1TAS1R2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3584075-B1 LAMINATE MITSUI CHEMICALS INC (JP) 2024-06-05 EP disclosed
US-11964447-B2 Laminate MITSUI CHEMICALS, INC. (JP) 2024-04-23 US disclosed
US-11905348-B2 Ethylene/alpha-olefin/non-conjugated polyene copolymer, method for producing the same, and use thereof MITSUI CHEMICALS, INC. (JP) 2024-02-20 US disclosed
EP-3584074-B1 LAMINATE MITSUI CHEMICALS INC (JP) 2023-06-21 EP disclosed
EP-3424705-B1 LAMINATE AND APPLICATION FOR SAME MITSUI CHEMICALS INC (JP) 2023-03-22 EP disclosed
US-20220266568-A1 LAMINATE MITSUI CHEMICALS, INC. (JP) 2022-08-25 US disclosed
US-10975223-B2 Resin composition and use thereof MITSUI CHEMICALS, INC. (JP) 2021-04-13 US disclosed
EP-3770190-A1 ETHYLENE/& X3B1;-OLEFIN/NON-CONJUGATED POLYENE COPOLYMER, PRODUCTION METHOD THEREFOR, AND USE Mitsui Chemicals, Inc. (JP) 2021-01-27 EP disclosed
US-20210009730-A1 ETHYLENE/alpha-OLEFIN/NON-CONJUGATED POLYENE COPOLYMER, METHOD FOR PRODUCING THE SAME, AND USE THEREOF MITSUI CHEMICALS, INC. (JP) 2021-01-14 US disclosed
EP-3231842-B1 PROPYLENE-BASED RESIN COMPOSITION MITSUI CHEMICALS INC (JP) 2020-03-11 EP disclosed
US-7795194-B2 Synthetic lubricating oil and lubricating oil composition MITSUI CHEMICALS, INC. (JP) 2010-09-14 US disclosed
US-20100056691-A1 PROPYLENE RESIN COMPOSITION, PROCESS FOR PRODUCING PROPYLENE RESIN COMPOSITION, PROPYLENE POLYMER COMPOSITION, SHAPED ARTICLE PRODUCED OF THE PROPYLENE RESIN COMPOSITION, AND ELECTRIC WIRE MITSUI CHEMICALS, INC. 2010-03-04 US disclosed
US-20100000600-A1 THERMOPLASTIC RESIN COMPOSITION FOR SEALING SOLAR CELL, SHEET FOR SEALING SOLAR CELL AND SOLAR CELL MITSUI CHEMICALS, INC. 2010-01-07 US disclosed
EP-2085420-A1 POLYPROPYLENE RESIN FILM AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2009-08-05 EP disclosed
EP-2080784-A1 PROPYLENE RESIN COMPOSITION, METHOD FOR PRODUCING PROPYLENE RESIN COMPOSITION, PROPYLENE POLYMER COMPOSITION, MOLDED BODY MADE OF THE PROPYLENE RESIN COMPOSITION, AND ELECTRIC WIRE Mitsui Chemicals, Inc. (JP) 2009-07-22 EP disclosed
EP-2048194-A1 THERMOPLASTIC RESIN COMPOSITION FOR SOLAR CELL SEALING, SHEET FOR SOLAR CELL SEALING, AND SOLAR CELL Mitsui Chemicals, Inc. (JP) 2009-04-15 EP disclosed
US-20080220193-A1 Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those MITSUI CHEMICALS, INC. 2008-09-11 US disclosed
EP-1900758-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE COPOLYMER, PROPYLENE POLYMER, PROPYLENE POLYMER COMPOSITION, AND USE OF THOSE Mitsui Chemicals, Inc. (JP) 2008-03-19 EP disclosed
US-20060116303-A1 decene-ethylene copolymer, zirconium, titanium or hafnium fluorene-containing complexes, organometallics; improved high thermal oxidation stability, viscosity index, low-temperature viscosity properties and shear stability MITSUI CHEMICALS, INC. (JP) 2006-06-01 US disclosed
EP-1661921-A1 Synthetic lubricating oil and lubricating oil composition thereof Mitsui Chemicals, Inc. (JP) 2006-05-31 EP disclosed