Hydrochloric Acid

Hydrochloric Acid

SCHEMBL400800

CC(C)(C)c1cc2c(cc1C(C)(C)C)C([Zr+2](C1=CC=CC1)=C(c1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1)c1cc(C(C)(C)C)c(C(C)(C)C)cc1-2.[Cl-].[Cl-]

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.33
CES2 O00748 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
TAS1R2 Q8TE23 1/20 0.33
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
RBP4 P02753 1/20 0.32
CNR2 P34972 4/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL399908 0.97 RBP4 (0.32) CES2ACHETAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL399300 0.94 CCR2 (0.35) CES2ACHETAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL399658 0.94 TAS1R3 (0.31) CES2ACHETAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL400909 0.92 GAA (0.32) TAS1R3TAS1R1TAS1R2MEN1KMT2A
Hydrochloric Acid SCHEMBL401076 0.92 ALDH1A1 (0.35) TAS1R3TAS1R1TAS1R2RBP4CNR2
Hydrochloric Acid SCHEMBL397277 0.91 ALDH1A1 (0.34) RBP4ALDH1A1
Hydrochloric Acid SCHEMBL398228 0.91
Hydrochloric Acid SCHEMBL400905 0.90 CCR2 (0.33) MEN1KMT2AHTTRAB9A
Hydrochloric Acid SCHEMBL401023 0.90 ACHE (0.38) CES2ACHETAS1R3TAS1R1TAS1R2
Hydrochloric Acid SCHEMBL399730 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3231842-B1 PROPYLENE-BASED RESIN COMPOSITION MITSUI CHEMICALS INC (JP) 2020-03-11 EP disclosed
EP-3231842-A1 PROPYLENE-BASED RESIN COMPOSITION Mitsui Chemicals, Inc. (JP) 2017-10-18 EP disclosed
EP-2842972-B1 METHOD FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2017-08-30 EP disclosed
US-20170081509-A1 PROPYLENE-BASED RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2017-03-23 US disclosed
EP-3124506-A1 OLEFIN RESIN AND METHOD FOR PRODUCING SAME Mitsui Chemicals, Inc. (JP) 2017-02-01 EP disclosed
US-20160280819-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE-BASED COPOLYMER, PROPYLENE POLYMER, PROPYLENE-BASED POLYMER COMPOSITION, AND USE OF THOSE MITSUI CHEMICALS, INC. (JP) 2016-09-29 US disclosed
US-9382356-B2 Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those MITSUI CHEMICALS, INC. (JP) 2016-07-05 US disclosed
US-9340628-B2 Process for producing olefin polymer MITSUI CHEMICALS, INC. (JP) 2016-05-17 US disclosed
US-20150094434-A1 PROCESS FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS, INC. (JP) 2015-04-02 US disclosed
EP-2842972-A1 METHOD FOR PRODUCING OLEFIN POLYMER Mitsui Chemicals, Inc. (JP) 2015-03-04 EP disclosed
US-8101684-B2 Thermoplastic resin composition for sealing solar cell, sheet for sealing solar cell and solar cell MITSUI CHEMICALS, INC. (JP) 2012-01-24 US disclosed
EP-2275457-A2 Propylene polymer, propylene-based polymer composition, and use of these Mitsui Chemicals, Inc. (JP) 2011-01-19 EP disclosed
US-7863368-B2 Propylene resin composition, process for producing propylene resin composition, propylene polymer composition, shaped article produced of the propylene resin composition, and electric wire MITSUI CHEMICALS, INC. (JP) 2011-01-04 US disclosed
US-7795194-B2 Synthetic lubricating oil and lubricating oil composition MITSUI CHEMICALS, INC. (JP) 2010-09-14 US disclosed
US-20100056691-A1 PROPYLENE RESIN COMPOSITION, PROCESS FOR PRODUCING PROPYLENE RESIN COMPOSITION, PROPYLENE POLYMER COMPOSITION, SHAPED ARTICLE PRODUCED OF THE PROPYLENE RESIN COMPOSITION, AND ELECTRIC WIRE MITSUI CHEMICALS, INC. 2010-03-04 US disclosed
US-20100000600-A1 THERMOPLASTIC RESIN COMPOSITION FOR SEALING SOLAR CELL, SHEET FOR SEALING SOLAR CELL AND SOLAR CELL MITSUI CHEMICALS, INC. 2010-01-07 US disclosed
EP-2085420-A1 POLYPROPYLENE RESIN FILM AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2009-08-05 EP disclosed
US-20080220193-A1 Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those MITSUI CHEMICALS, INC. 2008-09-11 US disclosed
US-20060116303-A1 decene-ethylene copolymer, zirconium, titanium or hafnium fluorene-containing complexes, organometallics; improved high thermal oxidation stability, viscosity index, low-temperature viscosity properties and shear stability MITSUI CHEMICALS, INC. (JP) 2006-06-01 US disclosed
EP-1661921-A1 Synthetic lubricating oil and lubricating oil composition thereof Mitsui Chemicals, Inc. (JP) 2006-05-31 EP disclosed