Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4006834 | 0.87 | SLC6A9 (0.56) | ALDH1A1SLC6A9ROCK2ROCK1NPC1 | |
| SCHEMBL4000824 | 0.81 | SLC6A9 (0.49) | SLC6A9ROCK2ROCK1NPC1RAB9A | |
| SCHEMBL4006927 | 0.77 | SLC6A9 (0.49) | ALDH1A1SLC6A9ROCK2ROCK1NPC1 | |
| SCHEMBL4011286 | 0.75 | SLC6A9 (0.50) | SLC6A9 | |
| SCHEMBL18059055 | 0.75 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3717031 | 0.74 | SLC6A4 (0.43) | SLC6A9ROCK2ROCK1KMT2A | |
| SCHEMBL4010839 | 0.74 | SLC6A9 (0.51) | SLC6A9NPC1RAB9A | |
| SCHEMBL13753631 | 0.73 | MEN1 (0.63) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10099586 | 0.72 | GPR132 (0.60) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7480996 | 0.72 | RAB9A (0.56) | ALDH1A1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |