Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DHPS | P49366 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007725 | 0.89 | ADORA3 (0.39) | ADORA3GCGRMAPTSMN1; SMN2TSHR | |
| SCHEMBL4010060 | 0.89 | DPP4 (0.36) | ADORA3ADORA1GCGRDPP4DPP8 | |
| SCHEMBL8038540 | 0.81 | GCGR (0.45) | ADORA3ADORA1GCGRDPP4DPP8 | |
| SCHEMBL4010063 | 0.79 | CNR1 (0.41) | ADORA3MAPTCNR1SMN1; SMN2TSHR | |
| SCHEMBL4011472 | 0.78 | MAPT (0.39) | ADORA3GCGRMAPTSMN1; SMN2TSHR | |
| SCHEMBL4010057 | 0.77 | DPP4 (0.48) | ADORA3ADORA1GCGRDPP4DPP8 | |
| SCHEMBL4014162 | 0.77 | TSHR (0.38) | ADORA3ADORA1MAPTTP53CNR1 | |
| SCHEMBL4011136 | 0.75 | RAB9A (0.38) | MAPTTP53TSHRPRNPL3MBTL1 | |
| SCHEMBL4007716 | 0.75 | ADORA3 (0.39) | ADORA3MAPTTP53SMN1; SMN2TSHR | |
| SCHEMBL4011132 | 0.74 | DHPS (0.41) | ADORA3ADORA1MAPTDHPSHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |