Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 4/20 | 0.36 |
| ▸ | AKT2 | P31751 | 2/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557266 | 0.85 | ALDH1A1 (0.47) | — | |
| SCHEMBL4024568 | 0.74 | PAK1 (0.68) | CYP1A2CYP2D6PAK1PDGFRBMALT1 | |
| SCHEMBL4017146 | 0.73 | LMNA (0.40) | CYP1A2AKT1AKT2AKT3MALT1 | |
| SCHEMBL4017659 | 0.73 | LMNA (0.39) | AKT1AKT2AKT3MALT1 | |
| SCHEMBL4016473 | 0.72 | PAK1 (0.65) | CYP1A2CYP2D6PAK1PDGFRBSUV39H1 | |
| SCHEMBL4582331 | 0.71 | CYP1A2 (0.50) | CYP1A2CYP2D6PAK1PDGFRBAKT1 | |
| SCHEMBL4023930 | 0.70 | ALDH1A1 (0.42) | — | |
| SCHEMBL4017236 | 0.68 | CYP1A2 (0.47) | CYP1A2CYP2D6PDGFRBAKT1AKT2 | |
| SCHEMBL4024856 | 0.68 | PAK1 (0.67) | CYP1A2CYP2D6PAK1PDGFRBMALT1 | |
| SCHEMBL4017652 | 0.68 | CYP1A2 (0.43) | CYP1A2CYP2D6PAK1SUV39H1PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | claimed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | claimed |