Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 5/20 | 0.36 |
| ▸ | AKT2 | P31751 | 5/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 5/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019437 | 0.84 | GPR119 (0.42) | GPR119AKT1 | |
| SCHEMBL4017659 | 0.80 | LMNA (0.39) | LMNAHTTSMN1; SMN2HRH1HRH3 | |
| SCHEMBL4021867 | 0.73 | MAPT (0.58) | LMNAHTTSMN1; SMN2HRH1HRH3 | |
| SCHEMBL4016468 | 0.73 | CYP1A2 (0.44) | CYP1A2AKT1AKT2AKT3MALT1 | |
| SCHEMBL4017150 | 0.71 | SMYD3 (0.56) | LMNAHTTSMN1; SMN2AKT1AKT2 | |
| SCHEMBL4018922 | 0.66 | LMNA (0.45) | LMNAHTTSMN1; SMN2ALDH1A1HRH1 | |
| SCHEMBL29230268 | 0.65 | LMNA (0.59) | LMNAHTTSMN1; SMN2HRH1HRH3 | |
| SCHEMBL6528468 | 0.64 | LMNA (0.73) | LMNAHTTSMN1; SMN2CYP1A2HRH1 | |
| Hydrochloric Acid SCHEMBL2797475 | 0.64 | LMNA (0.65) | LMNAHTTSMN1; SMN2HRH1HRH3 | |
| SCHEMBL2795640 | 0.64 | LMNA (0.64) | LMNAHTTSMN1; SMN2CLK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | claimed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | claimed |