Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | KIF5B | P33176 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 2/20 | 0.39 |
| ▸ | ATP4B | P51164 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013308 | 0.86 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BPTGDR2 | |
| SCHEMBL4013847 | 0.85 | MAPK14 (0.46) | HTR1AADRA1DADRA1AADRA1BPTGDR2 | |
| SCHEMBL4011946 | 0.84 | NR4A2 (0.49) | HTR1APTGDR2PDE4DMAPK14KDM4E | |
| SCHEMBL3509876 | 0.82 | RET (0.43) | HTR1AADRA1DADRA1AADRA1BRET | |
| SCHEMBL4013567 | 0.80 | PIK3CD (0.57) | HTR1AADRA1DADRA1AADRA1BPTGDR2 | |
| SCHEMBL4009254 | 0.80 | NR1H2 (0.47) | HTR1APTGDR2PDE4DMAPK14KDM4E | |
| SCHEMBL4012181 | 0.78 | PTGDR2 (0.45) | HTR1APTGDR2PDE4DNPC1RAB9A | |
| SCHEMBL4020656 | 0.77 | PTGDR2 (0.41) | HTR1APTGDR2PDE4DMAPK14KDM4E | |
| SCHEMBL4013386 | 0.76 | PTGDR2 (0.39) | HTR1AADRA1DADRA1AADRA1BPTGDR2 | |
| SCHEMBL4011501 | 0.76 | NR1H2 (0.55) | HTR1AADRA1DADRA1AADRA1BKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |