Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162091 | 0.85 | ALDH1A1 (0.38) | CYP17A1ALDH1A1TSHRNPSR1GPR174 | |
| SCHEMBL740789 | 0.81 | HTT (0.35) | ALDH1A1TSHRESR1HIF1AHPGD | |
| SCHEMBL7531055 | 0.81 | THRB (0.41) | ALDH1A1 | |
| SCHEMBL20237261 | 0.79 | PKM (0.41) | ALDH1A1NPSR1 | |
| SCHEMBL6741031 | 0.79 | ALDH1A1 (0.50) | CYP17A1ALDH1A1TSHRNPSR1GPR174 | |
| Phenol SCHEMBL3097283 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRGPR174ESR1HPGD | |
| SCHEMBL4194202 | 0.71 | HPGD (0.54) | ALDH1A1TSHRHIF1AHPGD | |
| SCHEMBL27544183 | 0.71 | THRB (0.40) | CYP17A1ALDH1A1TSHRNPSR1FFAR1 | |
| SCHEMBL548111 | 0.70 | RAB9A (0.37) | ALDH1A1HPGD | |
| SCHEMBL685869 | 0.70 | KMT2A (0.33) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097152-A1 | MULTIFUNCTIONAL ACRYLATES USED AS CROSS-LINKERS IN DENTAL AND BIOMEDICAL SELF-ETCHING BONDING ADHESIVES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-08-06 | — | — | WO | claimed |
| US-4774035-A | WEAR RESISTANCE | CAMELOT INDUSTRIES CORPORATION (US) | 1988-09-27 | — | — | US | disclosed |
| EP-0134300-B1 | METHOD OF PREPARING MICRO-CAPSULES | THREE BOND CO., LTD. (JP) | 1988-03-16 | — | — | EP | disclosed |