SCHEMBL8162091

SCHEMBL8162091

C=C(C)COC(C)Oc1ccc(C(CC)c2ccc(OC(C)OCC(=C)C)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
CYP17A1 P05093 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
LTB4R Q15722 4/20 0.34
LTB4R2 Q9NPC1 4/20 0.34
FFAR1 O14842 1/20 0.33
SLC7A5 Q01650 1/20 0.32
GPR174 Q9BXC1 1/20 0.32
MAPT P10636 1/20 0.31
BCHE P06276 1/20 0.31
TYR P14679 1/20 0.31
ACHE P22303 1/20 0.31
POLB P06746 1/20 0.31
CNR2 P34972 1/20 0.31
ESR1 P03372 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10870364 0.87 POLB (0.38) ALDH1A1GPR174POLB
SCHEMBL548111 0.86 RAB9A (0.37) ALDH1A1MAPTPOLB
SCHEMBL4017597 0.85 CYP17A1 (0.37) ALDH1A1TSHRCYP17A1NPSR1LTB4R
SCHEMBL9181136 0.82 MTNR1A (0.42) ALDH1A1GPR174
SCHEMBL2153398 0.81 MAPT (0.37) ALDH1A1NPSR1GPR174MAPTACHE
SCHEMBL2248368 0.80 POLB (0.40) ALDH1A1MAPTPOLB
SCHEMBL6741031 0.79 ALDH1A1 (0.50) ALDH1A1TSHRCYP17A1NPSR1FFAR1
SCHEMBL6655593 0.79 THRB (0.42) ALDH1A1FFAR1POLB
SCHEMBL6551445 0.79 KMT2A (0.56) TSHRPOLB
SCHEMBL3107707 0.78 SMN1; SMN2 (0.40) NPSR1GPR174POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6037408-A KIT HAVING PLURALITY OF CHAMBERS INCLUDING PREACCELERATED REACTION MIXTURE COMPRISING MONOMERIC 2,2-BIS(4(METHACRYLOXYETHOXY)PHENYL) PROPANE AND ACCELERATOR, ORGANIC PEROXIDE CURING AGENT, FILLER IN SEPARATE CHAMBERS UPAT GMBH & CO. (DE) 2000-03-14 US claimed
EP-0583471-B1 PHOTOPOLYMERIZABLE ADHESIVE JAPAN INST ADVANCED DENTISTRY (JP) 1997-09-17 EP disclosed
EP-0583471-A1 PHOTOPOLYMERIZABLE ADHESIVE JAPAN INSTITUTE OF ADVANCED DENTISTRY (JP) 1994-02-23 EP disclosed
US-4774035-A WEAR RESISTANCE CAMELOT INDUSTRIES CORPORATION (US) 1988-09-27 US disclosed
US-4764497-A HYDROLYSIS OF ORGANOSILICON COMPOUND CORE AND ORGANIC METALLIC COMPOUND TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1988-08-16 US disclosed
EP-0255716-A2 Process of producing toners for developing electrostatic images and the said toners DAINIPPON INK AND CHEMICALS, INC. (JP) 1988-02-10 EP disclosed
US-4567030-A Amorphous, spherical inorganic compound and process for preparation thereof TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-01-28 US disclosed