Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 6/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.42 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1620491 | 0.85 | ALDH1A1 (0.47) | ALDH1A1CA1CA2TSHRKDM4E | |
| SCHEMBL9027918 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRKDM4ETDP1L3MBTL1 | |
| SCHEMBL2843121 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ETDP1L3MBTL1 | |
| SCHEMBL27702945 | 0.82 | CA1 (0.47) | ALDH1A1CA1CA2TSHRKDM4E | |
| SCHEMBL31538163 | 0.82 | CA1 (0.47) | ALDH1A1CA1CA2TSHRKDM4E | |
| SCHEMBL269268 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CA1CA2TSHRKDM4E | |
| SCHEMBL31474876 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CA1CA2TSHRKDM4E | |
| SCHEMBL2436416 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TSHRKDM4ETDP1L3MBTL1 | |
| SCHEMBL16020868 | 0.81 | L3MBTL1 (0.43) | ALDH1A1CA1CA2KDM4ETDP1 | |
| SCHEMBL3840934 | 0.79 | MCL1 (0.47) | ALDH1A1CA1CA2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213396-B | Indole-2-ketone compound and preparation method and application thereof | 深圳市乐土生物医药有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-114213396-A | Indole-2-ketone compound and preparation method and application thereof | 深圳市乐土生物医药有限公司 | 2022-03-22 | — | — | CN | disclosed |
| EP-2970339-B1 | 1-HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | LILLY CO ELI (US) | 2017-08-16 | — | — | EP | disclosed |
| US-9617285-B2 | 1-hydroxy-benzooxaboroles as antiparasitic agents | ELI LILLY AND COMPANY (US) | 2017-04-11 | — | — | US | disclosed |
| CN-105051048-B | 1-hydroxy-benzoxaboroles as antiparasitic agents | 伊莱利利公司 | 2017-03-15 | — | — | CN | disclosed |
| EP-2970339-A1 | 1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | Eli Lilly and Company (US) | 2016-01-20 | — | — | EP | disclosed |
| US-20150353581-A1 | 1-HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | ELI LILLY AND COMPANY (US) | 2015-12-10 | — | — | US | disclosed |
| CN-105051048-A | 1-hydroxy-benzoxaboroles as antiparasitic agents | LILLY CO ELI | 2015-11-11 | — | — | CN | disclosed |
| WO-2014149793-A1 | 1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | ELI LILLY AND COMPANY (US) | 2014-09-25 | — | — | WO | disclosed |
| US-8569516-B2 | Compounds and methods for fluorescent labeling | ELITECH HOLDING B.V. (NL) | 2013-10-29 | — | — | US | disclosed |
| EP-1466176-A4 | COMPOUNDS AND METHODS FOR FLUORESCENT LABELING | EPOCH BIOSCIENCES INC (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007098336-A2 | COMPOUNDS AND METHODS FOR FLUORESCENT LABELING | EPOCH BIOSCIENCES, INC. (US) | 2007-08-30 | — | — | WO | disclosed |
| US-7112684-B2 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2006-09-26 | — | — | US | disclosed |
| US-20060204990-A1 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2006-09-14 | — | — | US | disclosed |
| US-20050277144-A1 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2005-12-15 | — | — | US | disclosed |
| US-6972339-B2 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2005-12-06 | — | — | US | disclosed |
| US-20050176066-A1 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2005-08-11 | — | — | US | disclosed |
| US-20050171340-A1 | COMPOUNDS AND METHODS FOR FLUORESCENT LABELING | EPOCH BIOSCIENCES, INC. (US) | 2005-08-04 | — | — | US | disclosed |
| EP-1466176-A2 | COMPOUNDS AND METHODS FOR FLUORESCENT LABELING | Epoch Biosciences, Inc. (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003023357-A2 | COMPOUNDS AND METHODS FOR FLUORESCENT LABELING | EPOCH BIOSCIENCES, INC. (US) | 2003-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176066-A1 | Compounds and methods for fluorescent labeling | HLCS, GLB1, TUBB | ALDH1A1 218/4885CA1 3267/4885CA2 4235/4885 |
| US-20060204990-A1 | Compounds and methods for fluorescent labeling | GLB1, HLCS, PFAS | ALDH1A1 445/4885CA1 3257/4885CA2 4361/4885 |
| US-20050171340-A1 | COMPOUNDS AND METHODS FOR FLUORESCENT LABELING | HLCS, GLB1, TUBB | ALDH1A1 218/4885CA1 3267/4885CA2 4235/4885 |
| US-20050277144-A1 | Compounds and methods for fluorescent labeling | HLCS, GLB1, TUBB | ALDH1A1 218/4885CA1 3267/4885CA2 4235/4885 |
| US-20150353581-A1 | 1-HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | HAO1, CYP8B1, KMO | ALDH1A1 518/4885CA1 3913/4885CA2 1429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.