Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012449 | 1.00 | PKM (0.49) | PKMSMN1; SMN2HSD17B10CHEK1ALDH1A1 | |
| SCHEMBL1078882 | 0.83 | CYP4F2 (0.51) | PKMSMN1; SMN2HSD17B10ALDH1A1LMNA | |
| SCHEMBL4802900 | 0.81 | TSHR (0.45) | SMN1; SMN2HSD17B10ALDH1A1LMNAKMT2A | |
| SCHEMBL10813508 | 0.81 | TSHR (0.36) | SMN1; SMN2HSD17B10ALDH1A1KMT2ATDP1 | |
| SCHEMBL10511460 | 0.81 | ALDH1A1 (0.40) | PKMSMN1; SMN2HSD17B10ALDH1A1LMNA | |
| SCHEMBL29225340 | 0.78 | ALDH1A1 (0.64) | ALDH1A1LMNAKMT2ATDP1L3MBTL1 | |
| SCHEMBL16111244 | 0.78 | KMT2A (0.52) | PKMSMN1; SMN2HSD17B10ALDH1A1LMNA | |
| SCHEMBL7963890 | 0.78 | CYP3A4 (0.45) | PKMSMN1; SMN2HSD17B10ALDH1A1LMNA | |
| SCHEMBL23500951 | 0.77 | RAB9A (0.49) | SMN1; SMN2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10362177 | 0.76 | MAOA (0.36) | KMT2ATDP1GAAL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015180-A2 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |