Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014400 | 0.85 | ADORA2A (0.41) | MEN1KMT2AADORA2BADORA3ADORA2A | |
| SCHEMBL4019166 | 0.85 | NOD1 (0.37) | MEN1KMT2AADORA2BADORA3ADORA1 | |
| SCHEMBL4293285 | 0.78 | BRD4 (0.39) | DPP4 | |
| SCHEMBL4283981 | 0.78 | TPH1 (0.34) | ADORA2BADORA2AADORA1DPP4CASR | |
| SCHEMBL4016921 | 0.77 | ADORA2B (0.41) | ADORA2BADORA3ADORA2AADORA1LMNA | |
| SCHEMBL4284310 | 0.77 | KDM1A (0.54) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL4019325 | 0.76 | LMNA (0.42) | ALDH1A1LMNAHPGDHTT | |
| SCHEMBL4295147 | 0.75 | MAOB (0.40) | LMNAHTT | |
| SCHEMBL4291739 | 0.74 | KDM1A (0.60) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4285483 | 0.73 | MEN1 (0.54) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009088518-A1 | A2B ADENOSINE RECEPTOR ANTAGONISTS FOR THE TREATMENT OF CANCER | CV THERAPEUTICS, INC. (US) | 2009-07-16 | — | — | WO | disclosed |