Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 11/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992770 | 0.84 | CXCR4 (0.47) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL14478353 | 0.79 | CXCR4 (0.57) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL15651459 | 0.78 | CXCR4 (0.77) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL16887825 | 0.78 | CXCR4 (0.52) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL1258489 | 0.75 | CXCR4 (0.92) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL3153045 | 0.73 | ALDH1A1 (0.88) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL3897416 | 0.73 | ALDH1A1 (0.64) | HRH3ALDH1A1SIGMAR1LMNAHSD11B1 | |
| SCHEMBL14312192 | 0.73 | CXCR4 (0.49) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL14640062 | 0.72 | CXCR4 (0.78) | CXCR4HRH3MEN1CHRM2CHRM1 | |
| SCHEMBL8038136 | 0.72 | SIGMAR1 (0.62) | CXCR4HRH3MEN1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557205-B2 | For improving contrast of X-ray, ultrasound, radionuclide and magnetic resonance images | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2009-07-07 | — | — | US | disclosed |
| US-20060069249-A1 | For improving contrast of X-ray, ultrasound, radionuclide and magnetic resonance images | HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069249-A1 | For improving contrast of X-ray, ultrasound, radionuclide and magnetic resonance images | SON, SPIN3, SHROOM3 | CXCR4 3116/4885HRH3 1985/4885MEN1 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.