Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455855 | 0.97 | TSHR (0.62) | TSHRALOX15ADORA2AADORA3ADORA2B | |
| SCHEMBL12216379 | 0.90 | NPC1 (0.51) | TSHRALOX15ADORA2AADORA3ADORA2B | |
| SCHEMBL4467732 | 0.89 | MAPK1 (0.56) | TSHRALOX15ADORA2AADORA3ADORA2B | |
| SCHEMBL4027746 | 0.87 | ALOX15 (0.60) | TSHRALOX15ADORA2AADORA3ADORA2B | |
| SCHEMBL15908091 | 0.86 | ADORA2A (0.77) | TSHRALOX15ADORA2AADORA3ADORA2B | |
| SCHEMBL4029619 | 0.86 | ADORA2A (0.77) | TSHRALOX15ADORA2AADORA3ADORA2B | |
| SCHEMBL1830032 | 0.86 | ADORA2A (0.77) | TSHRALOX15ADORA2AADORA3ADORA2B | |
| SCHEMBL6334711 | 0.86 | ADORA2A (0.77) | TSHRALOX15ADORA2AADORA3ADORA2B | |
| SCHEMBL16790688 | 0.85 | ADORA3 (0.46) | TSHRALOX15ADORA2AADORA3ADORA2B | |
| SCHEMBL29364346 | 0.85 | ALOX15 (0.62) | TSHRALOX15ADORA2AADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213283-B1 | Biphenyl-substituted triazines as light stabilisers | CIBA HOLDING INC (CH) | 2009-04-29 | — | — | EP | disclosed |
| EP-1213283-B1 | Biphenyl-substituted triazines as light stabilisers | CIBA HOLDING INC (CH) | 2009-04-29 | — | — | EP | disclosed |
| US-6919454-B2 | Biphenyl-substituted triazines | CIBA SPECIALTY CHEMICALS CORP. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20050019281-A1 | Biphenyl-substituted triazines | FLETCHER IAN JOHN (CH) | 2005-01-27 | — | — | US | disclosed |
| US-6841670-B2 | High thermal stability, are used as stabilizers for organic polymers to counter damage thereto caused by light, oxygen and heat, as light stabilizers for textile fiber materials and as sunscreens for the human skin. | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-01-11 | — | — | US | disclosed |
| US-20030045444-A1 | Biphenyl-substituted triazines | FLETCHER IAN JOHN (CH) | 2003-03-06 | — | — | US | disclosed |
| US-6468958-B2 | LIGHT, OXYGEN AND HEAT RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-10-22 | — | — | US | disclosed |
| EP-0815089-B1 | BIPHENYL-SUBSTITUTED TRIAZINES AS LIGHT STABILIZER | CIBA SC HOLDING AG (CH) | 2002-09-25 | — | — | EP | disclosed |
| EP-1213283-A2 | Biphenyl-substituted triazines as light stabilisers | Ciba SC Holding AG (CH) | 2002-06-12 | — | — | EP | disclosed |
| US-20010039341-A1 | Biphenyl-Substituted Triazines | FLETCHER IAN JOHN (CH) | 2001-11-08 | — | — | US | disclosed |
| US-6255483-B1 | USEFUL AS LIGHT STABILIZERS FOR TEXTILE FIBER MATERIALS AND SUNSCREENS FOR HUMAN SKIN | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-03 | — | — | US | disclosed |
| US-5998116-A | TRIAZINE UV ABSORBERS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0815089-A1 | BIPHENYL-SUBSTITUTED TRIAZINES AS LIGHT STABILIZER | Ciba SC Holding AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996028431-A1 | BIPHENYL-SUBSTITUTED TRIAZINES AS LIGHT STABILIZER | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1996-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050019281-A1 | Biphenyl-substituted triazines | TYR, AHR, CUTA | TSHR 3041/4885ALOX15 259/4885ADORA2A 3231/4885 |
| US-20030045444-A1 | Biphenyl-substituted triazines | TYR, CYP1B1, NFE2L2 | TSHR 3355/4885ALOX15 265/4885ADORA2A 3364/4885 |
| US-20010039341-A1 | Biphenyl-Substituted Triazines | TYR, CYP1B1, NFE2L2 | TSHR 3355/4885ALOX15 265/4885ADORA2A 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.