Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862266 | 0.82 | TRPV4 (0.50) | NPC1RAB9ATRPV4ALDH1A1CYP1A2 | |
| SCHEMBL5528618 | 0.81 | L3MBTL1 (0.46) | NPC1RAB9ASLC22A12ALDH1A1CYP1A2 | |
| SCHEMBL302695 | 0.81 | ALDH1A1 (0.53) | NPC1RAB9ASLC22A12ALDH1A1CYP1A2 | |
| SCHEMBL30753930 | 0.80 | ALDH1A1 (0.50) | NPC1RAB9ATRPV4SLC22A12ALDH1A1 | |
| SCHEMBL162306 | 0.80 | ALDH1A1 (0.50) | NPC1RAB9ATRPV4SLC22A12ALDH1A1 | |
| SCHEMBL646910 | 0.80 | TRPV4 (0.47) | TRPV4SLC22A12MAPTEPAS1 | |
| SCHEMBL2570257 | 0.79 | SLC22A12 (0.47) | TRPV4SLC22A12ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22980481 | 0.79 | TRPV4 (0.53) | TRPV4ALDH1A1LMNAHTR6CCR4 | |
| SCHEMBL4739158 | 0.78 | RAB9A (0.59) | NPC1RAB9AALDH1A1CYP3A4MAPT | |
| SCHEMBL4972108 | 0.77 | CYP1A2 (0.43) | TRPV4SLC22A12ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819668-B1 | NOVEL 2-CYANO-3-(HALO)ALKOXY-BENZENESULFONAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-05-26 | — | — | EP | disclosed |
| US-7563921-B2 | 2-cyano-3(halo)alkoxy-benzenesulfonamide compounds for combating animal pests | BASF AKTIENGESELLSCHAFT (DE) | 2009-07-21 | — | — | US | disclosed |
| US-7544637-B2 | 2-cyano-3(halo)alkoxy-benzenesulfonamide compounds for combating animal pests | BASF AKTIENGESELLSCHAFT (DE) | 2009-06-09 | — | — | US | disclosed |
| US-20080306297-A1 | NOVEL 2-CYANO-3(HALO)ALKOXY-BENZENESULFONAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-12-11 | — | — | US | disclosed |
| US-20080063678-A1 | Novel 2-Cyano-3(Halo)Alkoxy-Benzenesulfonamide Compounds for Combating Animal Pests | BASF AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | US | disclosed |
| EP-1819668-A2 | NOVEL 2-CYANO-3-(HALO)ALKOXY-BENZENESULFONAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-22 | — | — | EP | disclosed |
| US-20070071782-A1 | 2-Cyanobenzenesulfonamides for combating animal pests | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-29 | — | — | US | disclosed |
| EP-1670752-A1 | 2-CYANOBENZENESULFONAMIDES FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2006056433-A2 | NOVEL 2-CYANO-3-(HALO)ALKOXY-BENZENESULFONAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-01 | — | — | WO | disclosed |
| WO-2005035486-A1 | 2-CYANOBENZENESULFONAMIDES FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2005-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070071782-A1 | 2-Cyanobenzenesulfonamides for combating animal pests | MSR1, CHRM2, CBS | NPC1 2328/4885RAB9A 1561/4885TRPV4 2509/4885 |
| US-20080306297-A1 | NOVEL 2-CYANO-3(HALO)ALKOXY-BENZENESULFONAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | CBR3, CNPY3, CNPY2 | NPC1 1655/4885RAB9A 3014/4885TRPV4 1423/4885 |
| US-20080063678-A1 | Novel 2-Cyano-3(Halo)Alkoxy-Benzenesulfonamide Compounds for Combating Animal Pests | CNPY2, CNPY3, CBR3 | NPC1 1733/4885RAB9A 3212/4885TRPV4 1839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.