Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28979865 | 0.86 | ALDH1A1 (0.46) | ALDH1A1TSHRMEN1MAPTKMT2A | |
| SCHEMBL1952775 | 0.82 | ALDH1A1 (0.64) | PKMALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL145816 | 0.82 | KDM4E (0.52) | PKMALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL30073838 | 0.82 | KMT2A (0.42) | ALDH1A1TSHRCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL30073837 | 0.82 | KMT2A (0.42) | ALDH1A1TSHRCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL3781263 | 0.81 | TSHR (0.60) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9651424 | 0.81 | PKM (0.47) | PKMALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL11042208 | 0.81 | ALDH1A1 (0.49) | PKMALDH1A1TSHRCYP3A4TP53 | |
| SCHEMBL7824318 | 0.81 | TSHR (0.53) | PKMALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL10387706 | 0.81 | PKM (0.47) | PKMALDH1A1TSHRCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118771987-A | Preparation method of 2-nitro-3-methyl-5-chlorobenzoic acid | 帕潘纳(北京)科技有限公司 | 2024-10-15 | — | — | CN | claimed |
| CN-115583895-B | Synthetic method of 2-amino-5-chloro-N, 3-dimethylbenzamide | 苏州开元民生科技股份有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115583895-A | Synthetic method of 2-amino-5-chloro-N, 3-dimethylbenzamide | 苏州开元民生科技股份有限公司 | 2023-01-10 | — | — | CN | claimed |
| CN-118771987-A | Preparation method of 2-nitro-3-methyl-5-chlorobenzoic acid | 帕潘纳(北京)科技有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118771987-A | Preparation method of 2-nitro-3-methyl-5-chlorobenzoic acid | 帕潘纳(北京)科技有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118771987-A | Preparation method of 2-nitro-3-methyl-5-chlorobenzoic acid | 帕潘纳(北京)科技有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118439967-A | Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide | 宁夏贝利特生物科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-115583895-B | Synthetic method of 2-amino-5-chloro-N, 3-dimethylbenzamide | 苏州开元民生科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115583895-B | Synthetic method of 2-amino-5-chloro-N, 3-dimethylbenzamide | 苏州开元民生科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115583895-A | Synthetic method of 2-amino-5-chloro-N, 3-dimethylbenzamide | 苏州开元民生科技股份有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-115583895-A | Synthetic method of 2-amino-5-chloro-N, 3-dimethylbenzamide | 苏州开元民生科技股份有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-105859574-A | Synthesis method of 2-amino-5-chloro-N,3-dimethylbenzamide | 常州市阿曼特化工有限公司 | 2016-08-17 | — | — | CN | disclosed |
| EP-2591354-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | Ardelyx, Inc. (US) | 2013-05-15 | — | — | EP | disclosed |
| EP-2477976-A1 | QUINAZOLINONE DERIVATIVES AS VIRAL POLYMERASE INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2012-07-25 | — | — | EP | disclosed |
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
| US-20110230465-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) | 2011-09-22 | — | — | US | disclosed |
| WO-2011032277-A1 | QUINAZOLINONE DERIVATIVES AS VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230465-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2E | PKM 3668/4885ALDH1A1 1625/4885TSHR 3119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.