Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 7/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654647 | 0.90 | CNR2 (0.35) | KMT2AMAPT | |
| Carbamic Acid SCHEMBL3651238 | 0.87 | CA12 (0.33) | KMT2AMAPT | |
| SCHEMBL3651797 | 0.86 | TAS2R14 (0.39) | ABCC9ABCC8KCNJ11KCNJ8TAS2R14 | |
| SCHEMBL4129164 | 0.84 | HTR6 (0.38) | TAS2R14HTR6KMT2ALIMK2 | |
| SCHEMBL3652103 | 0.81 | KAT6A (0.36) | ABCC9ABCC8KCNJ11KCNJ8TAS2R14 | |
| SCHEMBL4029596 | 0.79 | HTR6 (0.37) | ABCC9ABCC8KCNJ11KCNJ8HTR6 | |
| SCHEMBL3799456 | 0.77 | SLC6A9 (0.34) | MAPT | |
| SCHEMBL3647498 | 0.74 | C1S (0.33) | — | |
| SCHEMBL4129168 | 0.74 | NAMPT (0.36) | ABCC9ABCC8KCNJ11KCNJ8HTR6 | |
| SCHEMBL3646770 | 0.74 | LMNA (0.30) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |