Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.47 |
| ▸ | CCND1 | P24385 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NMBR | P28336 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028879 | 0.82 | ALOX5 (0.47) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL4034270 | 0.79 | KMT2A (0.46) | MEN1KMT2AANO1ALDH1A1MAPT | |
| SCHEMBL4039235 | 0.79 | ALOX5 (0.44) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL5149351 | 0.78 | ANO1 (0.41) | MEN1KMT2AANO1ALDH1A1 | |
| SCHEMBL4034817 | 0.78 | ALOX5 (0.46) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL4034576 | 0.77 | ALOX5 (0.52) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL4029961 | 0.74 | ERAP2 (0.52) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL11829083 | 0.74 | MEN1 (0.55) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL21198341 | 0.71 | ANO1 (0.78) | ANO1 | |
| SCHEMBL4001473 | 0.70 | MEN1 (0.54) | CDK4CCND1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |