Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 3/20 | 0.43 |
| ▸ | CCND1 | P24385 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | NMBR | P28336 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039235 | 0.91 | ALOX5 (0.44) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4034817 | 0.88 | ALOX5 (0.46) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4034576 | 0.83 | ALOX5 (0.52) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4029965 | 0.82 | CDK4 (0.47) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL4632724 | 0.78 | GPR84 (0.40) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL3942280 | 0.78 | ALOX5 (0.49) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4035462 | 0.74 | KMT2A (0.41) | MEN1KMT2AMAPTNMBRCYP2D6 | |
| SCHEMBL4028875 | 0.73 | ALOX5 (0.47) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4028884 | 0.73 | ALOX5 (0.47) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4037073 | 0.70 | KMT2A (0.39) | ALOX5EPHX2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |