Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NMBR | P28336 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 3/20 | 0.42 |
| ▸ | CCND1 | P24385 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028879 | 0.88 | ALOX5 (0.47) | ALOX5EPHX2NMBRCDK4CCND1 | |
| SCHEMBL4039235 | 0.85 | ALOX5 (0.44) | ALOX5EPHX2NMBRCDK4CCND1 | |
| SCHEMBL4034576 | 0.81 | ALOX5 (0.52) | ALOX5EPHX2NMBRCDK4CCND1 | |
| SCHEMBL3936462 | 0.80 | ALOX5 (0.49) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4029965 | 0.78 | CDK4 (0.47) | NMBRCDK4CCND1MEN1KMT2A | |
| SCHEMBL4632724 | 0.78 | GPR84 (0.40) | ALOX5EPHX2NMBRCDK4CCND1 | |
| SCHEMBL4034821 | 0.75 | ALOX5 (0.46) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4034815 | 0.75 | ALOX5 (0.46) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4034799 | 0.73 | ALOX5 (0.49) | ALOX5EPHX2CDK4CCND1MEN1 | |
| SCHEMBL4031864 | 0.72 | MAPT (0.40) | NMBRMEN1KMT2ACCKBRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |