Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 4/20 | 0.38 |
| ▸ | NMBR | P28336 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | IL1RN | P18510 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028879 | 0.83 | ALOX5 (0.47) | ALOX5EPHX2MEN1KMT2ACDK4 | |
| SCHEMBL4034817 | 0.81 | ALOX5 (0.46) | ALOX5EPHX2MEN1KMT2ACDK4 | |
| SCHEMBL4039235 | 0.80 | ALOX5 (0.44) | ALOX5EPHX2MEN1KMT2ACDK4 | |
| SCHEMBL4029965 | 0.77 | CDK4 (0.47) | MEN1KMT2ACDK4CCND1NMBR | |
| SCHEMBL4632724 | 0.75 | GPR84 (0.40) | ALOX5EPHX2MEN1KMT2ACDK4 | |
| SCHEMBL4038448 | 0.68 | KMT2A (0.42) | MEN1KMT2ATACR1NMBRKDM4E | |
| SCHEMBL11829083 | 0.67 | MEN1 (0.55) | MEN1KMT2ACDK4CCND1TACR1 | |
| SCHEMBL4035462 | 0.66 | KMT2A (0.41) | MEN1KMT2ATACR1NMBRKDM4E | |
| SCHEMBL5149351 | 0.66 | ANO1 (0.41) | MEN1KMT2ATACR1KDM4ECYP2D6 | |
| SCHEMBL4737661 | 0.65 | ERAP2 (0.52) | ALOX5EPHX2MEN1KMT2ACDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |