Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2049060 | 1.00 | — | — | |
| Ethane SCHEMBL27547290 | 0.95 | TDP1 (0.80) | — | |
| Hydrochloric Acid SCHEMBL29268856 | 0.95 | — | — | |
| SCHEMBL27928984 | 0.94 | TDP1 (1.00) | — | |
| SCHEMBL1332279 | 0.94 | — | — | |
| SCHEMBL2020 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL23748751 | 0.91 | TDP1 (0.73) | — | |
| Hydrochloric Acid SCHEMBL28849153 | 0.91 | TDP1 (0.73) | — | |
| Hydrochloric Acid SCHEMBL28377416 | 0.91 | TDP1 (0.73) | — | |
| Dimethylamine SCHEMBL2052305 | 0.91 | TDP1 (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115784901-A | Diisopropylamine dichloroacetate and application thereof | 山东北大高科华泰制药有限公司 | 2023-03-14 | — | — | CN | disclosed |
| WO-2022059764-A1 | ION-EXCHANGEABLE LAYERED SILICATE SALT PARTICLES, OLEFIN POLYMERIZATION CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, METHOD FOR PRODUCING OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING OLEFIN POLYMER USING SAME | 日本ポリプロ株式会社 | 2022-03-24 | — | — | WO | disclosed |
| WO-2022059765-A1 | METHOD FOR PRODUCING ION-EXCHANGEABLE LAYERED SILICATE SALT PARTICLES, METHOD FOR PRODUCING OLEFIN POLYMERIZATION CATALYST COMPONENT, METHOD FOR PRODUCING OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING OLEFIN POLYMER USING SAME | 日本ポリプロ株式会社 | 2022-03-24 | — | — | WO | disclosed |
| CN-113631591-A | Method for producing catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization, and method for producing olefin polymer | 日本聚丙烯株式会社 | 2021-11-09 | — | — | CN | disclosed |
| WO-2020203274-A1 | PRODUCTION METHOD FOR CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PRODUCTION METHOD FOR CATALYST FOR OLEFIN POLYMERIZATION, AND PRODUCTION METHOD FOR OLEFIN POLYMER | 日本ポリプロ株式会社 | 2020-10-08 | — | — | WO | disclosed |
| EP-3061774-B1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, AND CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN (CO)POLYMER USING SAME | JAPAN POLYPROPYLENE CORP (JP) | 2018-04-18 | — | — | EP | disclosed |
| US-9751961-B2 | Catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin (co)polymer using the same | JAPAN POLYPROPYLENE CORPORATION (JP) | 2017-09-05 | — | — | US | disclosed |
| US-20160272736-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN (CO)POLYMER USING THE SAME | JAPAN POLYPROPYLENE CORPORATION (JP) | 2016-09-22 | — | — | US | disclosed |
| EP-3061774-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, AND CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN (CO)POLYMER USING SAME | Japan Polypropylene Corporation (JP) | 2016-08-31 | — | — | EP | disclosed |
| US-20090069171-A1 | Catalysts for olefin polymerization, process for production of the catalysts, and method for preservation thereof | JAPAN POLYPROPYLENE CORPORATION (JP) | 2009-03-12 | — | — | US | disclosed |
| EP-1881012-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION, PROCESS FOR PRODUCTION OF THE CATALYSTS, AND METHOD FOR PRESERVATION THEREOF | Japan Polypropylene Corporation (JP) | 2008-01-23 | — | — | EP | disclosed |