Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.64 |
| ▸ | MTOR | P42345 | 1/20 | 0.64 |
| ▸ | ADK | P55263 | 1/20 | 0.64 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30231261 | 1.00 | NISCH (0.64) | NISCHMTORADKCYP2A6CYP3A4 | |
| SCHEMBL24575932 | 0.84 | MTOR (0.46) | NISCHMTORADKCYP2A6CYP3A4 | |
| SCHEMBL24575959 | 0.80 | MAPK1 (0.48) | NISCHMTORADKCYP2A6CYP3A4 | |
| 2-Phenylimidazole SCHEMBL27904708 | 0.80 | NISCH (0.84) | NISCHMTORADKCYP3A4ALDH1A1 | |
| 2-Phenylimidazole SCHEMBL8901 | 0.79 | NISCH (1.00) | NISCHMTORADKCYP3A4ALDH1A1 | |
| 2-Phenylimidazole SCHEMBL9719773 | 0.79 | NISCH (1.00) | NISCHMTORADKCYP3A4ALDH1A1 | |
| 2-Phenylimidazole SCHEMBL27922661 | 0.78 | NISCH (0.81) | NISCHMTORADKCYP3A4ALDH1A1 | |
| 2-Phenylimidazole SCHEMBL11072040 | 0.77 | NISCH (0.95) | NISCHMTORADKCYP3A4ALDH1A1 | |
| SCHEMBL16777437 | 0.77 | NISCH (0.72) | NISCHMTORADKCYP3A4ALDH1A1 | |
| 2-Phenylimidazole SCHEMBL5796856 | 0.77 | NISCH (0.95) | NISCHMTORADKCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3914600-B1 | THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2024-08-07 | — | — | EP | claimed |
| CN-110511395-B | Inorganic-organic hybrid material of polyacid-based silver complex, preparation method and application | 吉林化工学院 | 2021-07-16 | — | — | CN | claimed |
| CN-110511395-A | The Inorganic-Organic Hybrid Material and preparation method and application of polyacid base silver complex | JILIN INST CHEMICAL TECH | 2019-11-29 | — | — | CN | claimed |
| CN-101379065-A | Imidazopyridine derivatives inhibiting protein kinase activity, method for the preparation thereof and pharmaceutical composition containing same | CRYSTALGENOMICS INC (KR) | 2009-03-04 | — | — | CN | claimed |
| EP-4570317-A2 | COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE | Intervet International B.V. (NL) | 2025-06-18 | — | — | EP | disclosed |
| US-12227485-B2 | Compounds useful for the treatment of infection with Mannheimia haemolytica or Histophilus somni | INTERVET INC. (US) | 2025-02-18 | — | — | US | disclosed |
| US-12157717-B2 | Compounds for the treatment of bovine or swine respiratory disease | INTERVET INC. (US) | 2024-12-03 | — | — | US | disclosed |
| US-12077488-B2 | Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection | INTERVET INC. (US) | 2024-09-03 | — | — | US | disclosed |
| CN-110072844-B | Compounds for the treatment of infection by Mannheimia haemolytica or histophilus somni | 英特维特国际股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | UNIV CALIFORNIA (US) | 2023-05-11 | — | — | US | disclosed |
| EP-4125861-A2 | PROTEIN-PROTEIN INTERACTION STABILIZERS | The Regents of the University of California (US) | 2023-02-08 | — | — | EP | disclosed |
| US-20230000813-A1 | COMPOUND FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE | INTERVET INC. (US) | 2023-01-05 | — | — | US | disclosed |
| US-4537969-A | AZOLE-SUBSTITUTED SATURATED HETEROCYCLIC CARBOXALDEHYDE ACETALS;INTERMEDIATES FOR 6-AMIDINOPENICILLINS | HOFFMANN-LA ROCHE INC. (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0148283-A1 | Novel penicillanic acid derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-07-17 | — | — | EP | disclosed |
| US-4499097-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-02-12 | — | — | US | disclosed |
| US-4431653-A | ANTIBIOTICS; BACTERICIDES; SSYNERGISTIC WITH AMINO ACID DERIVATIVE | HOFFMANN-LA ROCHE INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4281005-A | XANTHINE OXIDASE INHIBITORS AND AS ANTIHYPERTENSIVE | MERCK & CO., INC. (US) | 1981-07-28 | — | — | US | disclosed |
| US-4179512-A | XANTHINE OXIDASE INHIBITORS, HYPOTENSIVE | MERCK & CO., INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4110456-A | ANTIHYPERTENSIVE | MERCK & CO., INC. (US) | 1978-08-29 | — | — | US | disclosed |
| US-4058614-A | HYPOTENSIVE, XANTHINE OXIDASE ENZYME INHIBITOR | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12077488-B2 | Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection | SORD, HEXD, SNRPD1 | NISCH 1007/4885MTOR 3864/4885ADK 3545/4885 |
| US-12227485-B2 | Compounds useful for the treatment of infection with Mannheimia haemolytica or Histophilus somni | SORD, HEXD, SNRPD1 | NISCH 605/4885MTOR 3220/4885ADK 4002/4885 |
| US-12157717-B2 | Compounds for the treatment of bovine or swine respiratory disease | PIGS, BTD, PPARD | NISCH 419/4885MTOR 1088/4885ADK 3200/4885 |
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | HSPBP1, HSPA8, HSPH1 | NISCH 3933/4885MTOR 2210/4885ADK 3710/4885 |
| US-20230000813-A1 | COMPOUND FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE | PIGS, BTD, BRD1 | NISCH 605/4885MTOR 1105/4885ADK 3210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.