Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 7/20 | 0.63 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.63 |
| ▸ | HTR3B | O95264 | 3/20 | 0.63 |
| ▸ | HTR3A | P46098 | 3/20 | 0.63 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.63 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | NCF1 | P14598 | 1/20 | 0.57 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.57 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.55 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.55 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094312 | 1.00 | ADRB1 (0.63) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Bromide SCHEMBL8976702 | 0.98 | ADRB1 (0.61) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL3142642 | 0.98 | ADRB1 (0.61) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Bromide SCHEMBL6774826 | 0.98 | ADRB1 (0.61) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL24028031 | 0.92 | CHRNB2 (0.58) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL30307833 | 0.90 | CHRNB2 (0.57) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL14465246 | 0.89 | LTA4H (0.72) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5570604 | 0.88 | ADRB1 (0.77) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL18553773 | 0.86 | HTR6 (0.73) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7991421 | 0.84 | PIM1 (0.48) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118022687-A | Detection and removal of Hg2+/Hg+Ion adsorbent and preparation method thereof | 萍乡学院 | 2024-05-14 | — | — | CN | claimed |
| CN-116041300-B | 2, 2-Dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2024-04-26 | — | — | CN | claimed |
| CN-112111263-B | Preparation method of high-temperature-resistant clean fracturing fluid | 中国石油大学(华东) | 2023-03-28 | — | — | CN | claimed |
| CN-114367173-A | Liquid sponge desulfurizer | 北京荣华康都环境技术有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-114367169-A | Flue gas renewable desulfurization device and method | 北京荣华康都环境技术有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-114276315-A | Preparation method of 4- [4- [4- (4-hydroxyphenyl) piperazine-1-yl ] phenyl carbamate | 苏州汉德创宏生化科技有限公司 | 2022-04-05 | — | — | CN | claimed |
| US-20220024957-A1 | ANTICANCER ACTIVITIES OF A NOVEL FAMILY OF ETHACRYNIC ACID DERIVATIVES | UNIVERSITE EUROMEDITERRANEENNE DE FES (MA) | 2022-01-27 | — | — | US | claimed |
| EP-3887380-A1 | ANTI-CANCER ACTIVITIES OF A NEW FAMILY OF ETHACRYNIC ACID DERIVATIVES | Universite Euromediterraneenne De Fes (MA) | 2021-10-06 | — | — | EP | claimed |
| CN-110776897-B | Surfactant for low-permeability reservoir development and preparation method thereof | 中国海洋石油集团有限公司 | 2021-09-14 | — | — | CN | claimed |
| CN-112111263-A | Preparation method of high-temperature-resistant clean fracturing fluid | 中国石油大学(华东) | 2020-12-22 | — | — | CN | claimed |
| EP-1831206-A2 | N-SUBSTITUTED BENZIMIDAZOLYL C-KIT INHIBITORS AND COMBINATORIAL BENZIMIDAZOLE LIBRARY | OSI Pharmaceuticals, Inc. (US) | 2007-09-12 | — | — | EP | claimed |
| WO-2006060381-A2 | N-SUBSTITUTED BENZIMIDAZOLYL C-KIT INHIBITORS AND COMBINATORIAL BENZIMIDAZOLE LIBRARY | OSI PHARMACEUTICALS, INC. (US) | 2006-06-08 | — | — | WO | claimed |
| US-20060116402-A1 | N-substituted benzimidazolyl c-Kit inhibitors and combinatorial benzimidazole library | OSI PHARMACEUTICALS, INC. | 2006-06-01 | — | — | US | claimed |
| CN-1257163-C | Method for synthesizing 1-acetyl-4-(4-hydroxy pheny) piperazine | INST RADIATION MED AMMS PLA (CN) | 2006-05-24 | — | — | CN | claimed |
| US-7030150-B2 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2006-04-18 | — | — | US | claimed |
| CN-1616440-A | Method for synthesizing 1-acetyl-4-(4-hydroxy pheny) piperazine | INST RADIATION MED AMMS PLA (CN) | 2005-05-18 | — | — | CN | claimed |
| US-20030119754-A1 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2003-06-26 | — | — | US | claimed |
| WO-2002092575-A1 | BENZIMIDAZOLE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS, INC. (US) | 2002-11-21 | — | — | WO | claimed |
| EP-0229467-A1 | 1,5-Benzoxathiepin derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-07-22 | — | — | EP | claimed |
| EP-0150036-A1 | Azolyl-aryl-alkanole-derivatives, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-07-31 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024957-A1 | ANTICANCER ACTIVITIES OF A NOVEL FAMILY OF ETHACRYNIC ACID DERIVATIVES | ENDOD1, RPL15, COX15 | ADRB1 4459/4885HTR3E 635/4885HTR3B 1736/4885 |
| US-20030119754-A1 | Benzimidazole compounds and antiviral uses thereof | MAVS, ZC3HAV1, TIMM13 | ADRB1 3415/4885HTR3E 1875/4885HTR3B 3144/4885 |
| US-20060116402-A1 | N-substituted benzimidazolyl c-Kit inhibitors and combinatorial benzimidazole library | KIT, CHUK, TNNI3K | ADRB1 3656/4885HTR3E 3320/4885HTR3B 2852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.