Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP7 | P09237 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036850 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HPGDSMN1; SMN2MAPK1LMNA | |
| SCHEMBL4032496 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2MAPK1LMNA | |
| SCHEMBL4035404 | 0.83 | GAA (0.55) | ALDH1A1HPGDSMN1; SMN2MAPK1LMNA | |
| SCHEMBL1384878 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDSMN1; SMN2MAPK1LMNA | |
| SCHEMBL6192513 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDSMN1; SMN2MAPK1LMNA | |
| SCHEMBL4037009 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HPGDSMN1; SMN2MAPK1LMNA | |
| SCHEMBL4035342 | 0.75 | MAPK1 (0.59) | ALDH1A1HPGDSMN1; SMN2MAPK1LMNA | |
| SCHEMBL6230533 | 0.74 | MAPK1 (0.53) | ALDH1A1HPGDSMN1; SMN2MAPK1LMNA | |
| SCHEMBL4036762 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HPGDSMN1; SMN2MAPK1POLB | |
| SCHEMBL4036852 | 0.71 | MMP1 (0.50) | ALDH1A1SMN1; SMN2LMNAMMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | disclosed |