Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.44 |
| ▸ | RARG | P13631 | 7/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 4/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 4/20 | 0.42 |
| ▸ | RARB | P10826 | 4/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032561 | 0.88 | HSD17B1 (0.43) | HCAR3RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL23400674 | 0.82 | P2RY6 (0.43) | RAB9AKDM4EHTTNPC1SMN1; SMN2 | |
| SCHEMBL23399650 | 0.81 | SMN1; SMN2 (0.42) | RAB9AKDM4EGAAHTTNPC1 | |
| SCHEMBL2322010 | 0.72 | ALDH1A1 (0.42) | HCAR3RAB9AKDM4EPOLBGAA | |
| SCHEMBL31420284 | 0.71 | SMN1; SMN2 (0.54) | RXRARARGRARARARBRAB9A | |
| SCHEMBL23402126 | 0.71 | RIPK2 (0.48) | RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL22530233 | 0.69 | HCAR3 (0.43) | RXRAHCAR3RXRBRXRGRAB9A | |
| SCHEMBL22530587 | 0.68 | P2RY14 (0.49) | RXRAHCAR3RXRBRXRGRAB9A | |
| SCHEMBL2629322 | 0.67 | KMT2A (0.60) | RAB9AKDM4EPOLBGAAHTT | |
| SCHEMBL1640794 | 0.67 | HRH3 (0.58) | PHGDHRAB9ACHEK1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1767528-B1 | PROCESS FOR PRODUCING 5-HYDROXY-4-THIOMETHYLPYRAZOLE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2014-09-17 | — | — | EP | disclosed |
| US-7488831-B2 | Process for producing 5-hydroxy-4-thiomethylpyrazole compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |
| US-20070185334-A1 | Process for producing 5-hydroxy-4-thiomethylpyrazole compound | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-08-09 | — | — | US | disclosed |
| EP-1767528-A1 | PROCESS FOR PRODUCING 5-HYDROXY-4-THIOMETHYLPYRAZOLE COMPOUND | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2007-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185334-A1 | Process for producing 5-hydroxy-4-thiomethylpyrazole compound | CYP3A5, CYP4F11, GTF3C5 | RXRA 4595/4885RARG 4367/4885HCAR3 2411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.