Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188999 | 0.84 | MAPT (0.52) | FFAR1TSHRMEN1ALDH1A1MAPT | |
| SCHEMBL6370932 | 0.83 | CFD (0.53) | CFDHTR6TSHRCA12CA1 | |
| SCHEMBL4841851 | 0.83 | LOXL2 (0.51) | CFDHTR6SMN1; SMN2CA12CA1 | |
| SCHEMBL4031553 | 0.83 | POLB (0.56) | FFAR1TSHRMEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL4841840 | 0.82 | LOXL2 (0.50) | CFDHTR6SMN1; SMN2CA12CA1 | |
| SCHEMBL3200030 | 0.81 | FFAR1 (0.53) | FFAR1TSHRMEN1ALDH1A1MAPT | |
| SCHEMBL11441112 | 0.80 | DDX3X (0.53) | FFAR1HTR6TSHRMEN1ALDH1A1 | |
| SCHEMBL8276468 | 0.80 | ENPP2 (0.47) | CFDHTR6MAPTHTTLOXL2 | |
| SCHEMBL27501564 | 0.79 | HTR6 (0.47) | CFDHTR6MAPTHTTCA12 | |
| SCHEMBL28141068 | 0.78 | MTNR1A (0.61) | CFDHTR6TSHRMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885695-B1 | INDOLINE COMPOUNDS | FOURNIER LAB SA (FR) | 2009-02-25 | — | — | EP | disclosed |