Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768647 | 0.92 | MEN1 (0.51) | MCHR1MEN1KMT2ANPC1HSP90AA1 | |
| SCHEMBL4035492 | 0.91 | KMT2A (0.50) | NOS1MEN1KMT2ANPC1HSP90AA1 | |
| SCHEMBL4040533 | 0.82 | MEN1 (0.49) | MEN1KMT2ANPC1MAPTKDM4E | |
| SCHEMBL28033926 | 0.75 | PKM (0.49) | KMT2ANPC1HIF1AHDAC1HDAC2 | |
| SCHEMBL22497090 | 0.74 | NOS1 (0.56) | NOS1MEN1KMT2AHDAC1MAPT | |
| SCHEMBL30093244 | 0.74 | NOS1 (0.56) | NOS1MEN1KMT2AHDAC1MAPT | |
| SCHEMBL24097464 | 0.74 | MAPT (0.68) | NOS1MEN1KMT2ANPC1HIF1A | |
| SCHEMBL4040211 | 0.72 | MEN1 (0.49) | MEN1KMT2ANPC1ECE2AGTR1 | |
| SCHEMBL6695006 | 0.71 | MAPT (0.68) | NOS1MEN1KMT2ANPC1HIF1A | |
| SCHEMBL1134127 | 0.71 | CHRM2 (0.74) | MEN1KMT2AHDAC1HDAC2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |