Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033852 | 0.88 | TSHR (0.46) | LMNAALDH1A1TSHRPKMNAMPT | |
| SCHEMBL4032810 | 0.87 | LMNA (0.62) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL4035481 | 0.86 | TSHR (0.49) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4038410 | 0.86 | MAPT (0.48) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL4038385 | 0.84 | ALDH1A1 (0.57) | MEN1KMT2AKDM4EALDH1A1USP2 | |
| SCHEMBL4035100 | 0.84 | MAPT (0.50) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL4033312 | 0.83 | P2RX7 (0.45) | L3MBTL1POLB | |
| SCHEMBL4042590 | 0.82 | CHRM1 (0.43) | LMNAALDH1A1HPGDUSP2NAMPT | |
| SCHEMBL4042256 | 0.82 | POLB (0.46) | LMNAALDH1A1USP2POLBPKM | |
| SCHEMBL4035457 | 0.81 | CHRM5 (0.45) | MAPTLMNAPOLBNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |