Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035481 | 0.86 | TSHR (0.49) | ALDH1A1USP2KDM4ECHRM1KMT2A | |
| SCHEMBL4033852 | 0.86 | TSHR (0.46) | ALDH1A1PKMCHRM1 | |
| SCHEMBL4035235 | 0.86 | ALDH1A1 (0.76) | ALDH1A1USP2KDM4EPKMKMT2A | |
| SCHEMBL1383797 | 0.85 | PKM (0.60) | ALDH1A1USP2PKMKMT2AGAA | |
| SCHEMBL4042256 | 0.85 | POLB (0.46) | ALDH1A1USP2PKMCHRM1GAA | |
| SCHEMBL4042590 | 0.85 | CHRM1 (0.43) | ALDH1A1USP2CHRM1GAA | |
| SCHEMBL4037487 | 0.84 | MAPT (0.49) | ALDH1A1USP2KDM4EPKMKMT2A | |
| SCHEMBL4033312 | 0.84 | P2RX7 (0.45) | POLB | |
| SCHEMBL4036566 | 0.82 | ALDH1A1 (0.62) | ALDH1A1USP2KDM4EPKMKMT2A | |
| SCHEMBL4033365 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1CHRM1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |