Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 16/20 | 0.43 |
| ▸ | PPARG | P37231 | 10/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3483926 | 0.85 | FBP1 (0.41) | PTGDR2PPARAPPARGCYP1A2 | |
| SCHEMBL4035654 | 0.83 | PPARG (0.48) | PPARAPPARGPPARDCYP2C9CYP2C19 | |
| SCHEMBL4038642 | 0.77 | PPARA (0.54) | PPARAPPARGPPARDCYP2C9CYP1A2 | |
| SCHEMBL4033331 | 0.75 | PPARA (0.66) | PPARAPPARGPPARDCYP2C9CYP1A2 | |
| SCHEMBL11738947 | 0.73 | PPARG (0.72) | PPARAPPARGPPARDCYP1A2CYP2C19 | |
| SCHEMBL6701987 | 0.72 | KDM4E (0.48) | PTGDR2PPARAPPARGPPARDCYP2C9 | |
| SCHEMBL233843 | 0.72 | PPARA (0.47) | PTGDR2PPARAPPARGPPARDCYP1A2 | |
| SCHEMBL20014777 | 0.72 | PTGDR2 (0.43) | PTGDR2PPARAPPARGCYP2C9CYP1A2 | |
| SCHEMBL4035971 | 0.71 | MAP4K4 (0.53) | PPARAPPARGPPARDCYP2C9CYP2C19 | |
| SCHEMBL4033755 | 0.69 | KDM4E (0.48) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |