Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 13/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033474 | 0.90 | PKM (0.44) | P2RX7TRPA1PKMATMLMNA | |
| SCHEMBL4039505 | 0.88 | TRPA1 (0.43) | P2RX7TRPA1PKM | |
| SCHEMBL3890621 | 0.83 | PKM (0.40) | P2RX7TRPA1PKMATMLMNA | |
| SCHEMBL4841061 | 0.82 | ATM (0.45) | TRPA1PKMATMLMNATP53 | |
| SCHEMBL4841036 | 0.82 | ALDH1A1 (0.42) | TRPA1LMNA | |
| SCHEMBL4833963 | 0.82 | ALDH1A1 (0.42) | TRPA1LMNA | |
| SCHEMBL3840569 | 0.81 | TRPA1 (0.44) | P2RX7TRPA1 | |
| SCHEMBL4035782 | 0.81 | PKM (0.39) | P2RX7TRPA1PKMATMLMNA | |
| SCHEMBL3820156 | 0.81 | LMNA (0.43) | TRPA1PKMATMLMNATP53 | |
| SCHEMBL4842641 | 0.81 | GNRHR (0.39) | P2RX7TRPA1PKMATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885695-B1 | INDOLINE COMPOUNDS | FOURNIER LAB SA (FR) | 2009-02-25 | — | — | EP | disclosed |
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | P2RX7 908/4885TRPA1 368/4885PKM 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.