Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 10/20 | 0.35 |
| ▸ | CTSL | P07711 | 10/20 | 0.35 |
| ▸ | CTSS | P25774 | 7/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.33 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043843 | 0.93 | CTSK (0.41) | HSD17B10CTSKCTSLCTSSCTSB | |
| SCHEMBL4043869 | 0.92 | KCNQ1 (0.37) | HSD17B10ALDH1A1LMNAELOVL6 | |
| SCHEMBL4046940 | 0.90 | KDM4E (0.35) | HSD17B10CTSKCTSLCTSSCTSB | |
| SCHEMBL4046863 | 0.90 | SMYD3 (0.35) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4042524 | 0.89 | CHRNA7 (0.37) | HSD17B10SMYD3KDM4EALDH1A1LMNA | |
| SCHEMBL4051242 | 0.89 | CTSK (0.33) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4044711 | 0.88 | CTSK (0.47) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4044730 | 0.88 | LMNA (0.39) | HSD17B10CTSKKDM4EALDH1A1LMNA | |
| SCHEMBL4046913 | 0.87 | HSD17B10 (0.38) | HSD17B10CTSKCTSLCTSSSMYD3 | |
| SCHEMBL4051650 | 0.86 | HSD17B10 (0.36) | HSD17B10CTSKKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |