Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046989 | 0.93 | ALDH1A1 (0.38) | LMNAKDM4EALDH1A1MAPTELOVL6 | |
| SCHEMBL4040677 | 0.92 | CTSK (0.41) | LMNAKDM4EALDH1A1MAPTELOVL6 | |
| SCHEMBL4048312 | 0.91 | KCNQ1 (0.40) | LMNAKDM4EALDH1A1ELOVL6KCNQ1 | |
| SCHEMBL4051965 | 0.90 | MC4R (0.38) | LMNAKDM4EALDH1A1MAPTCTSK | |
| SCHEMBL4047844 | 0.90 | SMYD3 (0.35) | CTSK | |
| SCHEMBL4050093 | 0.89 | HTT (0.41) | LMNAALDH1A1MAPTELOVL6KCNQ1 | |
| SCHEMBL4048207 | 0.89 | HSD17B10 (0.36) | LMNAKDM4EALDH1A1MAPTELOVL6 | |
| SCHEMBL4051650 | 0.89 | HSD17B10 (0.36) | LMNAKDM4EALDH1A1MAPTELOVL6 | |
| SCHEMBL4045249 | 0.88 | CTSK (0.36) | LMNACTSKCCR1 | |
| SCHEMBL4041999 | 0.88 | HSD17B10 (0.36) | LMNAKDM4EALDH1A1MAPTELOVL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |