Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.39 |
| ▸ | CTSL | P07711 | 9/20 | 0.33 |
| ▸ | CTSS | P25774 | 7/20 | 0.33 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040779 | 0.93 | CTSV (0.34) | CTSKCTSLCTSSL3MBTL1MAPT | |
| SCHEMBL4045411 | 0.93 | PREP (0.33) | CTSKL3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL4043854 | 0.90 | CTSK (0.39) | CTSKCTSLCTSSCTSBL3MBTL1 | |
| SCHEMBL4046064 | 0.90 | SMN1; SMN2 (0.35) | CTSKCTSSCTSBL3MBTL1MAPT | |
| SCHEMBL4039790 | 0.89 | CTSK (0.39) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4042413 | 0.86 | CTSK (0.40) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4048016 | 0.86 | CTSK (0.46) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4040797 | 0.84 | CTSV (0.33) | CTSKCTSLCTSSL3MBTL1CTSV | |
| SCHEMBL4045316 | 0.83 | CTSK (0.40) | CTSKCTSLCTSSCTSBHTRA1 | |
| SCHEMBL4049252 | 0.83 | CTSK (0.39) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |