Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043622 | 0.93 | CTSK (0.39) | CTSVCTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL4045411 | 0.93 | PREP (0.33) | CTSKL3MBTL1ALDH1A1KDM4ECA12 | |
| SCHEMBL4040797 | 0.91 | CTSV (0.33) | CTSVCTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL4046064 | 0.90 | SMN1; SMN2 (0.35) | CTSSCTSKL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL4046671 | 0.86 | CTSK (0.41) | CTSVCTSLCTSSCTSK | |
| SCHEMBL4041817 | 0.83 | CTSL (0.33) | CTSVCTSLCTSSCTSK | |
| SCHEMBL4047097 | 0.83 | CTSL (0.33) | CTSVCTSLCTSSCTSKSMN1; SMN2 | |
| SCHEMBL4043854 | 0.83 | CTSK (0.39) | CTSVCTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL4040960 | 0.83 | PREP (0.32) | CTSKL3MBTL1KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL4042994 | 0.82 | CTSS (0.35) | CTSVCTSLCTSSCTSKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |