Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSV | O60911 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043670 | 0.91 | CTSV (0.37) | CTSSCTSVCTSLGCKF12 | |
| SCHEMBL4045645 | 0.90 | SMYD3 (0.34) | CTSSCTSLCTSBCTSKFKBP1A | |
| SCHEMBL4048072 | 0.89 | CTSV (0.39) | CTSSCTSVCTSLF12CTSK | |
| SCHEMBL4048674 | 0.89 | CTSS (0.37) | CTSSCTSVCTSLGCKF12 | |
| SCHEMBL4045088 | 0.88 | CTSS (0.37) | CTSSCTSVCTSLF12CTSB | |
| SCHEMBL4045926 | 0.86 | GPR132 (0.36) | CTSSCTSVCTSLGCKFKBP1A | |
| SCHEMBL4039394 | 0.85 | CTSL (0.42) | CTSSCTSVCTSLGCKF12 | |
| SCHEMBL4049892 | 0.84 | CTSS (0.37) | CTSSCTSVCTSLGCKF12 | |
| SCHEMBL4047756 | 0.83 | CTSL (0.38) | CTSSCTSVCTSLCTSKFKBP1A | |
| SCHEMBL4214125 | 0.83 | CTSS (0.38) | CTSSCTSVCTSLGCKF12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |