Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046543 | 0.90 | KCNQ1 (0.38) | GPR132CTSVCTSLCTSSGCK | |
| SCHEMBL4042764 | 0.90 | CTSK (0.38) | CTSLCTSSFKBP1A | |
| SCHEMBL4047237 | 0.89 | SMYD3 (0.35) | CTSLCTSSFKBP1A | |
| SCHEMBL4045208 | 0.89 | SMYD3 (0.35) | GPR132FKBP1A | |
| SCHEMBL4051046 | 0.88 | CTSV (0.39) | GPR132CTSVCTSLCTSSCPB2 | |
| SCHEMBL4047756 | 0.88 | CTSL (0.38) | GPR132CTSVCTSLCTSSCPB2 | |
| SCHEMBL4045653 | 0.87 | CTSS (0.38) | CTSVCTSLCTSSGCKHTRA1 | |
| SCHEMBL4041667 | 0.87 | HTRA1 (0.38) | GPR132CTSVCTSLCTSSCPB2 | |
| SCHEMBL4044172 | 0.86 | CTSS (0.36) | GPR132CTSVCTSLCTSSGCK | |
| SCHEMBL4042447 | 0.84 | CTSL (0.43) | CTSVCTSLCTSSGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |