Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047331 | 0.92 | CTSK (0.40) | CTSLCTSSCTSK | |
| SCHEMBL4042699 | 0.92 | CTSK (0.32) | CTSK | |
| SCHEMBL4052028 | 0.91 | CTSK (0.32) | CTSK | |
| SCHEMBL4051011 | 0.90 | HCRTR2 (0.34) | CTSVCTSLCTSS | |
| SCHEMBL4044323 | 0.88 | SMYD3 (0.33) | — | |
| SCHEMBL4048681 | 0.88 | CTSL (0.32) | CTSVCTSLCTSSCTSK | |
| SCHEMBL4048926 | 0.84 | CTSL (0.39) | CTSVCTSLCTSSCTSK | |
| SCHEMBL4051435 | 0.83 | HTRA1 (0.33) | CTSVCTSLCTSSCTSK | |
| SCHEMBL4041363 | 0.83 | CTSK (0.42) | CTSLCTSSCTSK | |
| SCHEMBL4043092 | 0.82 | CTSL (0.32) | CTSVCTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |