Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.32 |
| ▸ | PREP | P48147 | 2/20 | 0.30 |
| ▸ | FAP | Q12884 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047331 | 0.93 | CTSK (0.40) | CTSKPREPFAP | |
| SCHEMBL4044672 | 0.92 | CTSV (0.33) | CTSK | |
| SCHEMBL4042570 | 0.91 | CTSK (0.34) | CTSKPREPFAP | |
| SCHEMBL4043056 | 0.90 | HSD17B10 (0.36) | PREPFAP | |
| SCHEMBL4052028 | 0.90 | CTSK (0.32) | CTSK | |
| SCHEMBL4050322 | 0.89 | CTSK (0.34) | CTSKPREPFAP | |
| SCHEMBL4044199 | 0.89 | SMYD3 (0.34) | — | |
| SCHEMBL4044612 | 0.88 | PREP (0.33) | CTSKPREPFAP | |
| SCHEMBL4044808 | 0.86 | CTSK (0.36) | CTSKPREPFAP | |
| SCHEMBL4045553 | 0.86 | CTSK (0.34) | CTSKPREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |