Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045303 | 0.92 | CTSK (0.37) | SMYD3FKBP1A | |
| SCHEMBL4044199 | 0.92 | SMYD3 (0.34) | SMYD3F2FKBP1A | |
| SCHEMBL4045954 | 0.91 | SMYD3 (0.33) | SMYD3FKBP1A | |
| SCHEMBL4051011 | 0.90 | HCRTR2 (0.34) | SMYD3GCK | |
| SCHEMBL6236087 | 0.90 | SMYD3 (0.35) | SMYD3F2GCKFKBP1AGPR132 | |
| SCHEMBL4044672 | 0.88 | CTSV (0.33) | — | |
| SCHEMBL4043092 | 0.88 | CTSL (0.32) | GCK | |
| SCHEMBL4051435 | 0.87 | HTRA1 (0.33) | F2GPR132 | |
| SCHEMBL4048926 | 0.84 | CTSL (0.39) | — | |
| SCHEMBL4042904 | 0.83 | CTSK (0.39) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |